Hello,
I would suggest running the check disk command on the drive, type "cmd" into the start menu, right click the command prompt icon and select "run as administrator", in command prompt go to your storage drive "E:" by typing "CD E:/" then type "CHKDSK /F". This will check for badsectors and attempt to repair them.
I would also suggest running a virus scan just to elliminate the possibilty of a virus.
EDIT: If it doesn't work, take a look at this thread:
http://www.tomshardware.co.uk/forum/2810…reezes-computer. You may find your solution there.